Fmoc-Gly-Gly-(D-Phe)-Gly-CH2-O-CH2-Cbz

• UNSPSC Description:

  Fmoc-Gly-Gly-(D-Phe)-Gly-CH2-O-CH2-Cbz is a PROTAC linker and a maleimide-GGFG peptide linker. Fmoc-Gly-Gly-(D-Phe)-Gly-CH2-O-CH2-Cbz can be used in the synthesis of the Deruxtecan[1].

• Target Antigen:

  PROTAC Linkers

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/fmoc-gly-gly-d-phe-gly-ch2-o-ch2-cbz.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(OCC1=CC=CC=C1)COCNC(CNC([C@@H](CC2=CC=CC=C2)NC(CNC(CNC(OCC3C4=C(C=CC=C4)C5=C3C=CC=C5)=O)=O)=O)=O)=O

• Molecular Weight:

  735.78

• References & Citations:

  [1]NOGUCHI, Shigeru, et al. Method for selectively manufacturing antibody-drug conjugate. WO2017002776A1.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported