α-Glucosidase-IN-47

• UNSPSC Description:

  α-Glucosidase-IN-47 (compound 8H) is a non-competitive α-glucosidase (α-glucosidase) inhibitor with IC50 value is 38.2 μM and Ki value is 38.2 μM. α-Glucosidase-IN-47 can be used in diabetes research.[1].

• Target Antigen:

  Glycosidase

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/α-glucosidase-in-47.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(NC1=CC=C(F)C=C1)CSC2=NC3=CC=CC=C3C=C2C4=NC5=CC=CC=C5S4

• Molecular Weight:

  445.53

• References & Citations:

  [1]Ghomi MK, et al. Synthesis, in vitro potency of inhibition, enzyme kinetics and in silico studies of quinoline-based α-glucosidase inhibitors. Sci Rep. 2024 Jan 4;14(1):501.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported