Autotaxin-IN-6

• UNSPSC Description:

  Autotaxin-IN-6 (compound 23) is a potent autotaxin (ATX) inhibitor with an IC50 value of 30 nM. Autotaxin-IN-6 can reduce cell migration. Autotaxin-IN-6 can be used for researching anticancer[1].

• Target Antigen:

  LPL Receptor; Phosphodiesterase (PDE)

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;Metabolic Enzyme/Protease

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/autotaxin-in-6.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O[C@@H]1[C@]2([H])[C@@](CC[C@]3([C@@]2([H])CC[C@]3([H])[C@H](C)CCC(N4CCC(CC4)OC5=CC=C(C=C5)B(O)O)=O)C)([H])[C@@]6([C@](C[C@@H](CC6)O)([H])C1)C

• Molecular Weight:

  595.62

• References & Citations:

  [1]Clark JM, et al. Structure-Based Design of a Novel Class of Autotaxin Inhibitors Based on Endogenous Allosteric Modulators. J Med Chem. 2022 Apr 28;65(8):6338-6351.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2800898-98-8