σ1 Receptor/μ Opioid receptor modulator 1

• UNSPSC Description:

  σ1 Receptor/μ Opioid receptor modulator 1 (Compound 44) is a potent σ1 receptor antagonist and μ opioid receptor agonist with Kis of 1.86 nM and 2.1 nM, respectively.σ1 Receptor/μ Opioid receptor modulator 1 exhibits potent analgesic activity. σ1 Receptor/μ Opioid receptor modulator 1 can be used for the research of neuropathic pain[1].

• Target Antigen:

  Opioid Receptor; Sigma Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/σ1-receptor-μ-opioid-receptor-modulator-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CCC(N(CCN1CCC(CC2=CC=C(F)C=C2)CC1)C3=CC=C(OC)C=C3)=O

• Molecular Weight:

  398.51

• References & Citations:

  [1]Jiaying Xiong, et al. Piperidine propionamide as a scaffold for potent sigma-1 receptor antagonists and mu opioid receptor agonists for treating neuropathic pain. Eur J Med Chem. 2020 Apr 1;191:112144.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2412700-00-4