As-358 (hydrochloride)

• UNSPSC Description:

  As-358 (hydrochloride) has inhibitory effects against Ebola virus and Marburg virus with IC50s of 9.1 μM and 18.1 μM, as well as exhibits good in vivo safety[1].

• Target Antigen:

  Filovirus

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/as-358-hydrochloride.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(O[C@@H]1C[C@@H]2CC[C@]1(C2(C)C)C)CC[NH+]3CCCCC3.[Cl-]

• Molecular Weight:

  329.91

• References & Citations:

  [1]Sokolova AS, Yarovaya OI, Zybkina AV, et al. Monoterpenoid-based inhibitors of filoviruses targeting the glycoprotein-mediated entry process. Eur J Med Chem. 2020;207:112726.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2374723-26-7