FAAH/MAGL-IN-1

• UNSPSC Description:

  FAAH/MAGL-IN-1 (compound SIH 3) is a potent FAAH and MAGL inhibitor with IC50s of 31 nM and 29 nM, respectively. FAAH/MAGL-IN-1 has the potential for the research of neuropathic pain[1].

• Target Antigen:

  FAAH; MAGL

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease;Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/faah-magl-in-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(N/N=C1C(NC2=CC(Cl)=CC=C2\1)=O)C3=C(O)C=CC=C3Cl

• Molecular Weight:

  350.16

• References & Citations:

  [1]Jaiswal S, et al. Synthesis and evaluation of dual fatty acid amide hydrolase-monoacylglycerol lipase inhibition and antinociceptive activities of 4-methylsulfonylaniline-derived semicarbazones. Bioorg Med Chem. 2022; 60:116698.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported