TCS 21311

• Description:

  TCS 21311 is a potent JAK3 (Janus kinase 3) inhibitor. It shows high selectivity for JAK3 over JAK1, JAK2 and TYK2 with IC₅₀ values of 8 nM, 1017 nM, 2550 nM and 8055 nM respectively. It also inhibits GSK-3β, PKCα and PKCθ with IC₅₀ values of 3 nM, 13 nM and 68 nM, respectively.

• Shipping Conditions:

  RT

• Storage Conditions:

  -20ºC

• Shelf Life:

  36 months