Insulin Receptor beta Antibody

• Gene Name:

  [INSR]

• NCBI Gene ID:

  3643

• Reactivity:

  Human
  Predicted Reactivity: Dog (92%), Xenopus (100%)

• Storage Conditions:

  Store at -20 degree C. Stable for 12 months from date of receipt.

• Specificity:

  Insulin Receptor Antibody detects endogenous levels of Insulin Receptor.
  Tissue Specificity: Isoform Long and isoform Short are predominantly expressed in tissue targets of insulin metabolic effects: liver, adipose tissue and skeletal muscle but are also expressed in the peripheral nerve, kidney, pulmonary alveoli, pancreatic acini, placenta vascular endothelium, fibroblasts, monocytes, granulocytes, erythrocytes and skin. Isoform Short is preferentially expressed in fetal cells such as fetal fibroblasts, muscle, liver and kidney. Found as a hybrid receptor with IGF1R in muscle, heart, kidney, adipose tissue, skeletal muscle, hepatoma, fibroblasts, spleen and placenta (at protein level). Overexpressed in several tumors, including breast, colon, lung, ovary, and thyroid carcinomas.

• Other Gene Names:

  [INSR; INSR; HHF5; CD220; IR]

• Short Name:

  [Insulin Receptor beta]

• Other Product Names:

  [insulin receptor isoform Long preproprotein; Insulin receptor; insulin receptor; IR; insulin receptor]

• NCBI GI Number:

  119395736

• NCBI Accession Number:

  NP_000199.2

• NCBI GB Accession Number:

  NM_000208.2

• Uniprot Accession Number:

  P06213

• CAS Number:

  9007-83-4