MPIF-1/CCL23, Human (P.pastoris, His)

• UNSPSC Description:

  MPIF-1/CCL23 protein, Human (P.pastoris, His), a CC chemokine, is highly chemotactic for resting T cells and monocytes, mediates inflammatory and immune responses by binding to the chemokine receptor CCR1, inhibits myeloid progenitor cell formation, and has some pro-cancer effects. MPIF-1/CCL23 Protein, Human (P.pastoris, His) is a recombinant human MPIF-1/CCL23 (R46-N120) protein expressed by P. pastoris  with a his tag at the C-terminus[1].

• Type:

  Recombinant Proteins

• Assay Protocol:

  https://www.medchemexpress.com/cytokines/mpif-1-ccl23-protein-human-p-pastoris-his.html

• Molecular Weight:

  Approximately 9.9 kDa.

• References & Citations:

  [1]Jan Korbecki, et al. CC Chemokines in a Tumor: A Review of Pro-Cancer and Anti-Cancer Properties of the Ligands of Receptors CCR1, CCR2, CCR3, and CCR4. Int J Mol Sci. 2020 Nov 9;21(21):8412.|[2]Kyu Yeon Han, et al. CCL23 up-regulates expression of KDR/Flk-1 and potentiates VEGF-induced proliferation and migration of human endothelial cells. Biochem Biophys Res Commun. 2009 Apr 24;382(1):124-8.|[3]Son KN, et al. Human CC chemokine CCL23 enhances expression of matrix metalloproteinase-2 and invasion of vascular endothelial cells. Biochem Biophys Res Commun. 2006 Feb 10;340(2):498-504.|[4]Chih-Horng Shih, et al. CCL23/myeloid progenitor inhibitory factor-1 inhibits production and release of polymorphonuclear leukocytes and monocytes from the bone marrow. Exp Hematol. 2005 Oct;33(10):1101-8.

• Shipping Conditions:

  Room temperature