(22S,24E)-3β,22-Diacetoxylanosta-7,9(11),24-trien-26-oic acid

• UNSPSC Description:

  (22S,24E)-3β,22-Diacetoxylanosta-7,9(11),24-trien-26-oic acid (compound 15) is an antitubercular agent with MIC value of 12.5 μg/mL for Mycobacterium tuberculosis H37Ra. (22S,24E)-3β,22-Diacetoxylanosta-7,9(11),24-trien-26-oic acid shows cytotoxicity with IC50 value of 32 μM for Vero cells[1].

• Target Antigen:

  Bacterial

• Type:

  Natural Products

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/22s-24e-3β-22-diacetoxylanosta-7-9-11-24-trien-26-oic-acid.html

• Solubility:

  10 mM in DMSO

• Smiles:

  C[C@@]12C3=CC[C@](C)([C@@](CC4)([H])[C@H](C)[C@@H](OC(C)=O)C/C=C(C)/C(O)=O)[C@]4(C)C3=CC[C@@]1([H])C(C)([C@H](CC2)OC(C)=O)C

• Molecular Weight:

  554.76

• References & Citations:

  [1]Isaka M, et al. Antitubercular Lanostane Triterpenes from Cultures of the Basidiomycete Ganoderma sp. BCC 16642. J Nat Prod. 2016 Jan 22;79(1):161-9.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1846584-06-2