TdT/DNA Nucleotidylexotransferase (Acute Lymphoblastic Leukemia Marker)

• Gene Name:

  [DNTT]

• NCBI Gene ID:

  1791

• Reactivity:

  Human

• Storage Conditions:

  Antibody with azide: store at 2 to 8 degree C.
  Antibody without azide: store at -20 to -80 degree C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.

• Specificity:

  Terminal deoxynucleotidyltransferase (TdT) is a DNA polymerase which catalyzes the addition of deoxyribonucleotides onto the 3 termini of DNA. The human TdT gene maps to chromosome 10q24.1 and encodes a 510 amino acid protein. Human TdT is synthesized as a single chain peptide that elicits a minor preference for incorporation of deoxyribonucleotides over ribonucleotides forming DNA strands. TdT is present in immature thymocytes, some bone marrow cells, transformed pre-B and pre-T cell lines, and leukemia cells.

• Other Gene Names:

  [DNTT; DNTT; TDT; TDT; Terminal transferase]

• Short Name:

  [TdT/DNA Nucleotidylexotransferase]

• Other Product Names:

  [DNA nucleotidylexotransferase isoform 2; DNA nucleotidylexotransferase; DNA nucleotidylexotransferase; DNA nucleotidylexotransferase; Terminal addition enzyme; Terminal deoxynucleotidyltransferase]

• NCBI GI Number:

  63054852

• NCBI Accession Number:

  NP_001017520.1

• NCBI GB Accession Number:

  NP_001017520.1

• Uniprot Accession Number:

  P04053