(S)-Alaproclate (hydrochloride)

• UNSPSC Description:

  (S)-Alaproclate ((S)-A03) hydrochloride is a potent selective serotonin reuptake inhibitor (SSRI), which is used as an antidepressant agent. (S)-Alaproclate (hydrochloride) also produces a potent block of N-methyl-d-aspartate (NMDA) receptor currents in hippocampal neurons (IC50=1.1 μM) with a potent blocker of K+ currents[1].

• Target Antigen:

  Serotonin Transporter

• Type:

  Reference compound

• Related Pathways:

  Neuronal Signaling

• Applications:

  Neuroscience-Neurodegeneration

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/s-alaproclate-hydrochloride.html

• Smiles:

  N[C@@H](C)C(OC(C)(C)CC1=CC=C(Cl)C=C1)=O.Cl

• Molecular Weight:

  292.20

• References & Citations:

  [1]Svensson BE, et al. Alaproclate effects on voltage-dependent K+ channels and NMDA receptors: studies in cultured rat hippocampal neurons and fibroblast cells transformed with Kv1.2 K+ channel cDNA. Neuropharmacology. 1994 Jun;33(6):795-804.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  57469-92-8