Caspase 9 Mouse mAb

• Background:

  Caspase-9 is an initiator caspase, encoded by the CASP9 gene.Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Proteolytically cleaves poly (ADP-ribose) polymerase (PARP) .

• Description:

  Caspase-9 is an initiator caspase, encoded by the CASP9 gene. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Proteolytically cleaves poly (ADP-ribose) polymerase (PARP).

• Synonyms:

  APAF 3 antibody, Apoptosis related cysteine peptidase antibody, Apoptotic protease-activating factor 3 antibody, CASP 9 antibody

• Gene ID:

  842

• UniProt:

  P55211

• Cellular Locus:

  Cytosol,Mitochondrion,Nucleus

• Host:

  Mouse

• Species Reactivity:

  Human, Rat, Mouse

• Reactivity:

  Human, Rat, Mouse

• Immunogen:

  Synthetic Peptide

• Clonality:

  Monoclonal

• Isotype:

  IgG1

• Source:

  Mouse

• Applications:

  WB, IP, IF

• Validated Applications:

  WB, IP, IF

• Stability:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:1,000-5,000 IP 1:200 IF 1:100-200

• Molecular Weight:

  47 (51)kDa

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight:

  47 - (51) - kDa

• Subcellular Location:

  Cytosol, Mitochondrion, Nucleus

• Other Product Names:

  APAF 3 antibody, Apoptosis related cysteine peptidase antibody, Apoptotic protease-activating factor 3 antibody, CASP 9 antibody

• Gene ID (Human):

  842

• SwissProt (Human):

  P55211