MK-5108 (VX-689)

• Description:

  Aurora-A kinase inhibitor,highly selective

• Product Name Alternative:

  4-(3-chloro-2-fluorophenoxy)-1-[[6-(1,3-thiazol-2-ylamino)pyridin-2-yl]methyl]cyclohexane-1-carboxylic acid

• Field of Research:

  Cell Cycle Checkpoint Aurora Kinase Chromatin Epigenetics Aurora Kinase

• Purity:

  0.9691

• Form:

  A solid

• Solubility:

  ≥23.1 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O

• Smiles:

  C1CC(CCC1OC2=C(C(=CC=C2)Cl)F)(CC3=NC(=CC=C3)NC4=NC=CS4)C(=O)O

• Molecular Formula:

  C22H21ClFN3O3S

• Molecular Weight:

  461.94

• Shipping Conditions:

  Blue ice

• Storage Conditions:

  Store at -20°C.

• CAS Number:

  1010085-13-8