VX-680 (MK-0457,Tozasertib)

• Description:

  Aurora kinase inhibitor

• Product Name Alternative:

  N-[4-[4-(4-methylpiperazin-1-yl)-6-[(5-methyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl]sulfanylphenyl]cyclopropanecarboxamide

• Field of Research:

  Cell Cycle Checkpoint Aurora Kinase Chromatin Epigenetics Aurora Kinase

• Purity:

  0.9993

• Form:

  A solid

• Solubility:

  ≥23.25 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O

• Smiles:

  CC1=CC(=NN1)NC2=NC(=NC(=C2)N3CCN(CC3)C)SC4=CC=C(C=C4)NC(=O)C5CC5

• Molecular Formula:

  C23H28N8OS

• Molecular Weight:

  464.59

• Shipping Conditions:

  Blue ice

• Storage Conditions:

  Store at -20°C.

• CAS Number:

  639089-54-6