Thalidomide-pyrrolidine (hydrochloride)

• UNSPSC Description:

  Thalidomide-pyrrolidine hydrochloride (compound 18) is an E3 ligase ligand, and can be used for synthesis of PROTACs[1].

• Target Antigen:

  Ligands for E3 Ligase

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/androgen-receptor-degrader-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1NC(C(CC1)N2C(C3=C(C2=O)C=C(CNC4)C4=C3)=O)=O.[H]Cl

• Molecular Weight:

  335.74

• References & Citations:

  [1]Shao MW, et, al. Androgen receptor protein degraders with a tricyclic cereblon ligand. WO2021231927A1.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2616553-35-4