4,10-Dioxatri cyclo[5.2. 1.02.6]dec-8-ene-3,5-dione

• UNSPSC Description:

  4,10-Dioxatri cyclo[5.2. 1.02.6]dec-8-ene-3,5-dione is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

• Target Antigen:

  Nucleoside Antimetabolite/Analog

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/4-10-dioxatri-cyclo-5-2-1-02-6-dec-8-ene-3-5-dione.html

• Purity:

  97.0

• Solubility:

  DMSO : ≥ 100 mg/mL

• Smiles:

  C1=CC2C3C(C1O2)C(=O)OC3=O

• Molecular Weight:

  166.13

• References & Citations:

  [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C (Powder, sealed storage, away from moisture)

• Clinical Information:

  No Development Reported

• CAS Number:

  5426-09-5