VEGFR-2-IN-43

• UNSPSC Description:

  VEGFR-2-IN-43 (compound 16) is an orally active inhibitor of VEGFR2, with an IC50 of 39.91 μM. VEGFR-2-IN-43 can be used for wet age-related macular degeneration (w-AMD) disease research[1].

• Target Antigen:

  VEGFR

• Type:

  Reference compound

• Related Pathways:

  Protein Tyrosine Kinase/RTK

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer; Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/vegfr-2-in-43.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CCO[C@@H]1CN(C[C@H]1NC(C2=C(NC(/C=C3C(NC4=CC=C(C=C4\3)F)=O)=C2C)C)=O)C(CO)=O

• Molecular Weight:

  470.49

• References & Citations:

  [1]Xiu X, et al. Potential oral VEGFR2 inhibitors: Treatment of wet age-related macular degeneration. Bioorg Chem. 2024 Mar;144:107110.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported