GLP-1(7-36), amide (acetate)

• UNSPSC Description:

  GLP-1(7-36), amide acetate is a major intestinal hormone that stimulates glucose-induced insulin secretion from β cells.

• Target Antigen:

  GCGR

• Type:

  Peptides

• Related Pathways:

  GPCR/G Protein

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/GLP-17-36.html

• Purity:

  99.36

• Solubility:

  H2O : ≥ 100 mg/mL

• Smiles:

  CC(O)=O.N=C(NCCC[C@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC1=CNC2=CC=CC=C12)NC([C@@H](NC([C@@H](NC([C@H](CC3=CC=CC=C3)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@H](CC4=CC=C(O)C=C4)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC5=CC=CC=C5)NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@H](CC6=CN=CN6)N)=O)C)=O)CCC(O)=O)=O)=O)[C@@H](C)O)=O)=O)[C@@H](C)O)=O)CO)=O)CC(O)=O)=O)C(C)C)=O)CO)=O)CO)=O)=O)CC(C)C)=O)CCC(O)=O)=O)=O)CCC(N)=O)=O)C)=O)C)=O)CCCCN)=O)CCC(O)=O)=O)=O)[C@H](CC)C)=O)C)=O)=O)CC(C)C)=O)C(C)C)=O)CCCCN)=O)=O)C(N)=O)N.[x]

• Molecular Weight:

  3297.64 (free base)

• References & Citations:

  [1]Fujii Y et al. Ingestion of coffee polyphenols increases postprandial release of the active glucagon-like peptide-1(GLP-1(7-36)) amide in C57BL/6J mice. J Nutr Sci. 2015 Mar 3Int J Endocrinol. 2020 Jun 19;2020:1484321.|J Pharm Anal. 2024 Mar 24, 100968.|MAbs. Jan-Dec 2021;13(1):1893425.|Research Square Preprint. 2023 May 22.|Research Square Preprint. 2024 Jan 9.|Patent. US20200283424A1.|Patent. US20230278991A1.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)

• Clinical Information:

  No Development Reported

• CAS Number:

  1119517-19-9