7-Hydroxymethyl-10,11-MDCPT

• UNSPSC Description:

  7-Hydroxymethyl-10,11-MDCPT is a payload that can be used for ADC synthesis[1].

• Target Antigen:

  ADC Cytotoxin

• Type:

  Reference compound

• Related Pathways:

  Antibody-drug Conjugate/ADC Related

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/7-hydroxymethyl-10-11-mdcpt.html

• Solubility:

  10 mM in DMSO

• Smiles:

  OCC1=C2C(C(N3C2)=CC([C@](O)(C(OC4)=O)CC)=C4C3=O)=NC5=CC(OCO6)=C6C=C51

• Molecular Weight:

  422.39

• References & Citations:

  [1]Wadkins RM, et al. Hydrophilic camptothecin analogs that form extremely stable cleavable complexes with DNA and topoisomerase I. Cancer Res. 2004 Sep 15;64(18):6679-83.|[2]Cai JQ, Human anti-human HER3 antibodies and ADCs or drug conjugates for therapy, prevention and diagnosis of cancer or infection. 2023. WO2023143263

• Shipping Conditions:

  Blue Ice

• Clinical Information:

  No Development Reported

• CAS Number:

  428816-69-7