4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol

• UNSPSC Description:

  4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL), a significant metabolite of the carcinogenic nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, is linked to the development of lung cancer in smokers.

• Target Antigen:

  Endogenous Metabolite

• Type:

  Natural Products

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/4-_Methylnitrosamino_-1-_3-pyridyl_-1-butanol.html

• Smiles:

  O=NN(CCCC(C1=CC=CN=C1)O)C

• Molecular Weight:

  209.25

• References & Citations:

  [1]Elucidating the chemical structure of native 1-deoxysphingosine|[2]Hereditary sensory neuropathy type 1 is caused by the accumulation of two neurotoxic sphingolipids|[3]Analysis of sphingolipids in extracted human plasma using liquid chromatography electrospray ionization tandem mass spectrometry|[4]Ceramide sphingolipid signaling mediates Tumor Necrosis Factor (TNF)-dependent toxicity via caspase signaling in dopaminergic neurons

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  76014-81-8