Anti-Na+/K+-ATPase alpha1 Antibody

CAT: 0519-A00956Size: 100 µLDry Ice: NoHazardous: No

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CAT#:0519-A00956Size:100 µL

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Description

Boster Bio Anti-Na+/K+-ATPase alpha1 Antibody catalog # A00956. Tested in WB, IHC, IF, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Synonyms

Sodium/potassium-transporting ATPase subunit alpha-1; Na (+) /K (+) ATPase alpha-1 subunit;3.6.3.9; Sodium pump subunit alpha-1; ATP1A1

Gene Name

ATP1A1

UniProt

P05023

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human ATPase. AA range:5-54

Applications

WB, IHC, IF, ELISA

Purification

Immunogen affinity purified

Concentration

1 mg/mL

Form

Liquid

Function

This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

112896 MW

Gene Name Synonym

Sodium/potassium-transporting ATPase subunit alpha-1

Subcellular Location

Cell membrane; Multi-pass membrane protein. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

Isotype

IgG

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

UniProtKB · P05023

Sodium/potassium-transporting ATPase subunit alpha-1

AT1A1_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: P05023
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: ATP1A1
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: Na(+)/K(+) ATPase alpha-1 subunit
EC number: 7.2.2.13
Processing: —
Secondary accessions: B2RBR6, B7Z2T5, B7Z3U6, F5H3A1, Q16689, Q6LDM4, Q9UCN1, Q9UJ20, Q9UJ21

Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationPhosphoprotein

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingMagnesiumMetal-bindingNucleotide-bindingPotassiumSodium

Cellular component

Cell membraneCell projectionMembrane

Disease

Charcot-Marie-Tooth diseaseEpilepsyIntellectual disabilityNeurodegenerationNeuropathyPrimary hypomagnesemia

Biological process

Ion transportPotassium transportSodium transportSodium/potassium transportTransport

Molecular function

Translocase

Domain

TransmembraneTransmembrane helix

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