5,7,3'-Tri-O-methyl (-)-epicatechin

• UNSPSC Description:

  5,7,3' -tri-O-Methyl (-)-epicatechin (Compound 13) is a phospholipase Cγ1 (PLCγ1) inhibitor. 5,7,3' -tri-o-methyl (-)-epicatechin has a methylene dioxy benzene ring and can express inhibitory activity against PLCγ1. 5,7,3' -tri-O-Methyl (-)-epicatechin can be used in the study of chemotherapy and chemopexic agents for cancer [1].

• Target Antigen:

  Others

• Type:

  Natural Products

• Related Pathways:

  Others

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/5-7-3-tri-o-methyl-minus-epicatechin.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O[C@H]1[C@@H](C2=CC=C(O)C(OC)=C2)OC3=CC(OC)=CC(OC)=C3C1

• Molecular Weight:

  332.35

• References & Citations:

  [1]Lee JS, et al. Inhibition of phospholipase Cgamma1 and cancer cell proliferation by lignans and flavans from Machilus thunbergii. Arch Pharm Res. 2004 Oct;27(10):1043-7

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  97914-19-7