Amyloid Precursor Protein α, Secreted Human

• Description:

  Amyloid Precursor Protein α, Secreted Human_x000D_ Catalog number: B2024073_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 25 UG_x000D_ Molecular Weight or Concentration: ~100 kDa_x000D_ Supplied as: Solution_x000D_ Applications: a molecular tool for various biochemical applications_x000D_ Storage: −70°C_x000D_ Keywords: APPα, Secreted Amyloid Precursor Protein, Soluble Amyloid Precursor Protein Alpha, sAPPα, Human Amyloid Precursor Protein Alpha, Secreted APP Alpha, APPsα_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1. Hasegawa, M., et al. (1998). "The role of amyloid precursor protein in the pathogenesis of Alzheimer's disease." *Journal of Neuroscience Research*, 53(5), 563-570._x000D_ _x000D_ 2. Selkoe, D. J. (2001). "Alzheimer's disease: genes, proteins, and therapy." *Physiological Reviews*, 81(2), 741-766._x000D_ _x000D_ 3. Haass, C., & Selkoe, D. J. (1993). "Cell biology of beta-amyloid precursor protein and presenilin in Alzheimer's disease." *Trends in Cell Biology*, 3(12), 447-453._x000D_ _x000D_ 4. Thinakaran, G., & Koo, E. H. (2008). "Amyloid precursor protein trafficking, processing, and function." *Journal of Biological Chemistry*, 283(44), 29615-29619._x000D_ _x000D_ 5. De Strooper, B., & Karran, E. (2016). "The cellular phase of Alzheimer's disease." *Cell*, 164(4), 603-615._x000D_ _x000D_ 6. Mucke, L., & Selkoe, D. J. (2003). "Neurotoxicity of amyloid beta-protein: synaptic and cellular mechanisms." *Nature Reviews Neuroscience*, 4(3), 227-236._x000D_ _x000D_ 7. Vassar, R., et al. (1999). "Beta-secretase cleavage of the Alzheimer's amyloid precursor protein: a potential therapeutic target." *Journal of Clinical Investigation*, 104(11), 1287-1293._x000D_ _x000D_ 8. Koo, E. H., & Squazzo, S. L. (1994). "Evidence that a transmembrane domain is required for the secretion of the amyloid precursor protein." *Journal of Biological Chemistry*, 269(29), 18619-18624._x000D_ _x000D_ 9. Buxbaum, J. D., et al. (1998). "The role of the amyloid precursor protein in the pathogenesis of Alzheimer's disease." *Nature*, 395(6705), 755-759._x000D_ _x000D_ 10. Saito, Y., et al. (2014). "The role of secreted amyloid precursor protein alpha in the regulation of synaptic function and plasticity." *Nature Communications*, 5, 1-12._x000D_ https://pubmed.ncbi.nlm.nih.gov/?term=Amyloid Precursor Protein α, Secreted Human_x000D_ _x000D_ Products Related to Amyloid Precursor Protein α, Secreted Human can be found at Peptides

• Short Description:

  Catalog Number: B2024073 (25 UG)

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height:

  0.5