N-Oleoyl-L-Serine

• Description:

  N-Oleoyl-L-Serine (N-Oleoylserine) is an endogenous long-chain fatty acid amide that is a lipid modulator of bone remodeling and stimulates osteoclast apoptosis which can be used to study osteoporosis. N-Oleoyl-L-Serine showed high activity in an osteoblast proliferation assay.N-Oleoyl-L-Serine promotes osteoclast apoptosis by inhibiting Erk1/2 phosphorylation and expression of nuclear κB ligand (RANKL) receptor activator in bone marrow stromal cells and osteoblasts, which attenuates osteoclast populations.

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  369.54

• Molecular Formula:

  C21H39NO4

• Notes:

  Research use only, not for human use.

• Receptor:

  Apoptosis

• CAS Number:

  107743-37-3