Histone H2A (acetyl K9) Rabbit mAb

• Background:

  Eukaryotic histones are basic and water soluble nuclear proteins that form hetero-octameric nucleosome particles by wrapping 146 base pairs of DNA in a left-handed super-helical turn sequentially to form chromosomal fiber. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form the octamer; formed of two H2A-H2B dimers and two H3-H4 dimers, forming two nearly symmetrical halves by tertiary structure. Over 80% of nucleosomes contain the linker Histone H1, derived from an intronless gene, that interacts with linker DNA between nucleosomes and mediates compaction into higher order chromatin. Histones are subject to posttranslational modification by enzymes primarily on their N-terminal tails, but also in their globular domains. Such modifications include methylation, citrullination, acetylation, phosphorylation, sumoylation, ubiquitination and ADP-ribosylation.

• Description:

  This is a Histone H2A (acetyl K9) Rabbit mAb Acetyl-Specific Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  Histone H2A type 1-B/E Histone H2A.2 Histone H2A/a Histone H2A/m

• Gene ID:

  30128335

• Swiss Prot:

  P04908

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant protein

• Clonality:

  Monoclonal

• Conjugation:

  Unconjugated

• Type:

  Acetyl-Specific Antibody

• Applications:

  WB, ICC/IF, IHC

• Purification Method:

  ProA affinity purification

• Assay Type:

  Antibody

• Dilution:

  WB 1:500-1:1000, IHC 1:50-1:200, ICC 1:50-1:200

• Buffer:

  1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  14 kDa

• Host or Source:

  Rabbit