Recombinant Phospho-PTP1B (Ser352) Monoclonal Antibody

• Background:

  PTP1B is a tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response and mediates dephosphorylation of EIF2AK3/PERK; inactivating the protein kinase activity of EIF2AK3/PERK. During metaphase, PTP1B is phosphorylated by protein kinase C (PKC) at S352, which is also phosphorylated in response to osmotic stress, but do not markedly change PTP1B activity.

• Abbreviation:

  Phospho-PTP1B (Ser352)

• UniProt:

  P18031

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Phosphorylated human PTP1B (Ser352) peptide

• Target:

  PTPN; PTPN1; PTP1B

• Clonality:

  Monoclonal, Recombinant

• Clone:

  A801

• Conjugation:

  Unconjugated

• Applications:

  WB

• Field of Research:

  Signal Transduction; Cardiovascular

• Purification:

  Protein A purified

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  50 kDa

• Observed Molecular Weight:

  50 kDa

• Isotype:

  IgG, κ