Recombinant Phospho-Acetyl-CoA Carboxylase (Ser79) Monoclonal Antibody

• Background:

  Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. ACC-beta is thought to control fatty acid oxidation by means of the ability of malonyl-CoA to inhibit carnitine-palmitoyl-CoA transferase I, the rate-limiting step in fatty acid uptake and oxidation by mitochondria. ACC-beta may be involved in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. There is evidence for the presence of two ACC-beta isoforms.

• Abbreviation:

  Acetyl-CoA Carboxylase

• UniProt:

  Q13085; O00763

• Host:

  Rabbit

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  A synthetic peptide corresponding to residues around (Ser79) of Human Phospho-Acetyl-CoA Carboxylase

• Target:

  ACACA; ACAC; ACACAD; ACC; ACC1; ACCA; ACC

• Clonality:

  Monoclonal, Recombinant

• Clone:

  11A2

• Conjugation:

  Unconjugated

• Applications:

  WB; IHC

• Field of Research:

  Cardiovascular; Signal Transduction; Cancer; Metabolism

• Purification:

  Protein A

• Concentration:

  0.2 mg/mL

• Dilution:

  IHC 1:200-1:1000; WB 1:1000-1:15000

• Buffer:

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  266 kDa

• Observed Molecular Weight:

  266 kDa

• Isotype:

  IgG, κ