Recombinant Collagen II Monoclonal Antibody

• Background:

  This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene.

• Abbreviation:

  Collagen II

• UniProt:

  P02458

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Recombinant Human Collagen II protein

• Target:

  STL; collagen type; CO2A; COL2A; COL11A; Collagen; COL2A1; ANFH; AOM; COL11A3; SEDC; STL1; Alpha 1 type II collagen; Cartilage collagen; Chondrocalcin; CO2A1; Collagen II alpha 1 polypeptide; PIICP; PIINP; Collagen II; Collagen 2; collagen type 2; Alpha-1 type II collagen; CTX2

• Clonality:

  Monoclonal, Recombinant

• Clone:

  9A8

• Conjugation:

  Unconjugated

• Applications:

  WB

• Field of Research:

  Signal Transduction; Stem Cells

• Purification:

  Protein A

• Concentration:

  0.2 mg/mL

• Dilution:

  WB 1:1000-1:5000

• Buffer:

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  142 kDa

• Observed Molecular Weight:

  200 kDa

• Isotype:

  IgG, κ