Recombinant Phospho-Syk (Tyr525/526) Monoclonal Antibody

• Background:

  This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

• Abbreviation:

  Syk

• UniProt:

  P43405

• Host:

  Rabbit

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  A synthetic peptide corresponding to residues around (Tyr525/526) of Human Phospho-Syk

• Target:

  SYK; p72-Syk; spleen associated tyrosine kinase; Tyrosine-protein kinase SYK

• Clonality:

  Monoclonal, Recombinant

• Clone:

  8C4

• Conjugation:

  Unconjugated

• Applications:

  WB

• Field of Research:

  Cardiovascular; Signal Transduction; Immunology

• Purification:

  Protein A

• Concentration:

  0.2 mg/mL

• Dilution:

  WB 1:2000-1:10000

• Buffer:

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  72 kDa

• Observed Molecular Weight:

  72 kDa

• Isotype:

  IgG, κ