Products for Research Use Only
RegisterLogin

Recombinant AMPKβ1 Monoclonal Antibody

CAT: 0763-AN301259L-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0763-AN301259L-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK) . AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex.
Abbreviation
AMPKβ1
UniProt
Q9Y478
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant Human AMPKβ1 protein
Target
5'-AMP-activated protein kinase subunit beta; PRKAB; PRKAB1; AMPK; HAMPKb;5'-AMP-activated protein kinase subunit beta-1;5'-AMP-activated protein kinase subunit beta-1; AMPK; HAMPKb; AMPKβ1
Clonality
Monoclonal, Recombinant
Clone
5H6
Conjugation
Unconjugated
Applications
IHC
Field of Research
Signal Transduction; Cardiovascular; Cancer; Metabolism
Purification
Protein A
Concentration
0.2 mg/mL
Dilution
IHC 1:100-1:500
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG, κ

UniProtKB · Q9Y478

5'-AMP-activated protein kinase subunit beta-1

AAKB1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9Y478
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PRKAB1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
AMPK subunit beta-1, AMPKb
EC number
—
Processing
—
Secondary accessions
Q9UBV0, Q9UE20, Q9UEX2, Q9Y6V8
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Biological process

Fatty acid biosynthesisFatty acid metabolismLipid biosynthesisLipid metabolism

PTM

LipoproteinMyristatePhosphoprotein

Related Products

CatalogName
AN301866L-01Recombinant AMPK alpha 1+AMPK alpha 2 Monoclonal Antibody
AN303016L-01Recombinant AMPK alpha 1 Monoclonal Antibody
AN303017L-01Recombinant AMPK alpha 1/2 Monoclonal Antibody
AN302382L-01Recombinant AMPKα1 (Phospho Ser485) Monoclonal Antibody
AN303018L-01Recombinant AMPK alpha 2 Monoclonal Antibody
AN300369L-01Recombinant Phospho-AMPKα (Thr172) Monoclonal Antibody
AN301152L-01Recombinant Phospho-AMPK α1, 2 (Thr183, Thr172) Monoclonal Antibody
E-AB-22248-01AMPK alpha1 Monoclonal Antibody
E-AB-22125-01AMPK alpha1 Monoclonal Antibody
E-AB-66996-01AMPKα1 Polyclonal Antibody

Alternative Products

CatalogName
RAA00094-01AMPK α1 Recombinant Monoclonal Antibody
A5676AMPK beta 1 recombinant monoclonal antibody
A5008AMPK alpha 1 recombinant monoclonal antibody
A5025AMPK gamma 1 recombinant monoclonal antibody
RA10763-01AMPKα1 Monoclonal Antibody
ABM0072AMPK α1 Monoclonal Antibody
GTR18047748-01AMPKβ1 monoclonal antibody
HA750147AMPK alpha 1 Recombinant Rabbit monoclonal Antibody
GTR18520441-01AMPK gamma 1 Recombinant Rabbit Monoclonal Antibody
MB3322AMPK beta 1 monoclonal antibody

Popular Products