Recombinant Phospho-Smad3 (Ser423, Ser425) Monoclonal Antibody

• Background:

  The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.

• Abbreviation:

  Smad3

• UniProt:

  P84022

• Host:

  Rabbit

• Reactivity:

  Human; Mouse

• Immunogen:

  A synthetic peptide corresponding to residues around (Ser423, Ser425) of Human Phospho-Smad3

• Target:

  LDS; MAD; HSPC; JV15; MADH; MAD homolog; SMAD family member; Mothers against DPP homolog; Mothers against decapentaplegic homolog; hMAD; hSMAD; HSPC193; HsT17436; JV15-2; LDS1C; LDS3; MADH3; hMAD-3; hSMAD3; MAD homolog 3; Mad3; Mothers against decapentaplegic homolog 3; Mothers against DPP homolog 3; SMAD 3; SMAD family member 3; SMAD3; DKFZP586N0721; DKFZp686J10186; hMAD 3; JV15 2; JV152; MAD (mothers against decapentaplegic Drosophila) homolog 3; Mad homolog JV15 2; Mad protein homolog; MADH 3; MGC60396; SMA and MAD related protein 3; SMAD

• Clonality:

  Monoclonal, Recombinant

• Clone:

  6H9

• Conjugation:

  Unconjugated

• Applications:

  WB; IHC

• Field of Research:

  Signal Transduction; Epigenetics and Nuclear Signaling; Stem Cells; Cancer; Metabolism

• Purification:

  Protein A

• Concentration:

  0.2 mg/mL

• Dilution:

  IHC 1:200-1:1000; WB 1:2000-1:10000

• Buffer:

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  48 kDa

• Observed Molecular Weight:

  52 kDa

• Isotype:

  IgG, κ