Recombinant Angiopoietin-2/ANG 2 Monoclonal Antibody

• Background:

  Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal. Involved in the regulation of lymphangiogenesis.

• Abbreviation:

  ANGPT2

• UniProt:

  O15123

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Recombinant Human Angiopoietin-2/ANG 2 protein

• Target:

  Angiopoitin; ANGP; Ang; ANGPT2; AGPT2; ANG2; AGPT 2; ANG 2; angiopoietin 2; Angiopoietin 2a; Angiopoietin 2B; Angiopoietin2; angiopoietin-2a; angiopoietin-2B; angiopoitin 2; ANGP2; ANGPT 2; Tie2 ligand; Tie2-ligand; Angiopoietin-2; ANG-2; Agpt2; ANG2; Angiopoietin 2a; Angiopoietin 2B; Angiopoietin2; ANGPT 2; Angpt2; Tie2 ligand

• Clonality:

  Monoclonal

• Clone:

  6A6

• Conjugation:

  Unconjugated

• Applications:

  WB; ICC/IF; IP

• Field of Research:

  Cardiovascular

• Purification:

  Protein A

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:1000; ICC/IF 1:100-1:500; IP 0.2-1 μL/mg of lysate

• Buffer:

  0.2 μm filtered solution in PBS

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

• Calculated Molecular Weight:

  57 kDa

• Observed Molecular Weight:

  70 kDa

• Isotype:

  IgG