Purified Anti-Human CD123 Antibody[HI12H7]

• Background:

  CD123 is the 70 kD transmembrane α chain of the IL-3 receptor. Alone, CD123 binds IL-3 with low affinity; when CD123 associates with CDw131 (common β chain), it binds IL-3 with high affinity. CD123 does not transduce intracellular signals upon binding IL-3 and requires the β chain for this function. CD123 is expressed by myeloid precursors, macrophages, dendritic cells, mast cells, basophils, megakaryocytes, and some B cells.

• Abbreviation:

  CD123

• UniProt:

  P26951

• Host:

  Mouse

• Reactivity:

  Human

• Immunogen:

  Recombinant Human CD123 protein

• Target:

  IL3R, CD123, IL3RX, IL3RY, IL-3R&alpha, IL3RA, IL3RAY, hIL-3Ra, IL-3 Receptor alpha, IL-3 receptor subunit alpha, IL-3R subunit alpha, IL-3R subunitalpha, IL-3RA, IL-3R-alpha, IL-3Receptoralpha, IL-3Rα, IL-4Receptoralpha, IL-5Receptoralpha, IL-6Receptoralpha, IL-7Receptoralpha, Interleukin-3 receptor subunit alpha

• Clonality:

  Monoclonal

• Clone:

  HI12H7

• Conjugation:

  Unconjugated

• Applications:

  FCM

• Field of Research:

  Cytokine and Growth Factors, Immunology, Signal Transduction, CDs

• Purification:

  >98%, Protein A/G purified

• Concentration:

  ≥ 1 mg/mL

• Dilution:

  66

• Buffer:

  Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

• Isotype:

  Mouse IgG1, κ