Purified Anti-Human CD123 Antibody[HI8D7]

• Background:

  CD123 is the 70 kD transmembrane α chain of the IL-3 receptor. Alone, CD123 binds IL-3 with low affinity; when CD123 associates with CDw131 (common β chain), it binds IL-3 with high affinity. CD123 does not transduce intracellular signals upon binding IL-3 and requires the β chain for this function. CD123 is expressed by myeloid precursors, macrophages, dendritic cells, mast cells, basophils, megakaryocytes, and some B cells.

• Abbreviation:

  CD123

• Gene ID:

  3563

• UniProt:

  P26951

• Host:

  Mouse

• Reactivity:

  Human

• Immunogen:

  Recombinant Human CD123 protein

• Target:

  IL3RA; CD123; IL3R; IL3RAY; IL3RX; IL3RY; hIL-3Ra; IL-3 Receptor alpha; IL-3 receptor subunit alpha; IL-3R subunit alpha; IL-3R subunitalpha; IL-3RA; IL-3R-alpha; IL-3Receptoralpha; IL-3Rα; IL-4Receptoralpha; IL-5Receptoralpha; IL-6Receptoralpha; IL-7Receptoralpha; Interleukin-3 receptor subunit alpha; IL-3R&alpha

• Clonality:

  Monoclonal

• Clone:

  HI8D7

• Conjugation:

  Unconjugated

• Applications:

  FCM

• Field of Research:

  Immunology; Signal Transduction

• Purification:

  >98%, Protein A/G purified

• Concentration:

  ≥ 1 mg/mL

• Dilution:

  66

• Buffer:

  PBS, pH 7.2. Contains 0.05% proclin 300.

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

• Isotype:

  Mouse IgG1, κ