CD24 Antibody [30-F1] (APC)

• Background:

  CD24 is expressed in B cells until their terminal differentiation into plasma cells. It has been used widely as a marker to fractionate different B-lineage differentiation stages. CD24 has been found on a variety of other hematopoietic and neural cell types and is now classified as a costimulatory molecule. The CD24 molecule, also known as HSA, is composed mostly of carbohydrate with a protein core of only 31-35 amino acids in the human and 27 amino acids in the mouse. CD24 is now included in the large group of phosphatidylinositol-anchored membrane proteins. Studies with purified CD24 applied to latex beads have demonstrated a self-binding property suggesting that the molecule is capable of promoting homotypic aggregation, binding, and cell adhesion. This is supported by earlier observations of the blockade of B cell lymphoblast aggregation with an anti-CD24 monoclonal antibody. Recent studies of murine CD24 have assigned a role for CD24 as a ligand for P-selectin, a calcium-dependent lectin.

• NCBI Gene ID:

  12484

• Swiss Prot:

  P24807

• Accession Number:

  P24807

• Host:

  Rat

• Reactivity:

  Mouse

• Immunogen:

  Mouse thymus or spleen

• Clonality:

  Monoclonal

• Clone:

  [30-F1]

• Conjugation:

  APC

• Type:

  Primary Antibodies

• Field of Research:

  Immunology

• Concentration:

  0.1 mg/mL

• Buffer:

  Supplied in PBS/NaN3 and a stabilizing agent

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store vial at 2-8˚ C

• Fragment:

  IgG2c

• Specificity:

  CD24

• Applications Notes:

  CD24 Antibody [30-F1] for use in flow cytometry assays.

• Symbol:

  Cd24a

• NCBI Official Name:

  CD24a antigen

• NCBI Organism:

  Mus musculus

• Other Product Names:

  Heat stable antigen, HSA

• Tested Applications:

  IHC-P, IHC-Fr, ICC, Flow

• Physical Properties:

  Liquid