NK1.1 Antibody [PK136]

• Background:

  NK1.1, a member of the NKR-P1 family of cell surface receptors, is a type II integral membrane glycoprotein with a C-type lectin domain. It is expressed as a disulfide-linked homodimer on all NK cells as well as subsets of thymocytes and peripheral T lymphocytes in selected strains of mice (e.g., C57BL/6, NZB, and CE) . NK1.1 mediates cellular activation and differentiation, and is thought to have a particular role in generating Th2 cells. This product does not react with NK cells of BALB/c mice.

• NCBI Gene ID:

  17059

• Swiss Prot:

  P27814

• Accession Number:

  P27814

• Host:

  Mouse

• Reactivity:

  Mouse

• Immunogen:

  CE mouse spleen enriched for NK-1+ cells and bone marrow cells

• Clonality:

  Monoclonal

• Clone:

  [PK136]

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Innate Immunity

• Concentration:

  0.5 mg/mL

• Buffer:

  Supplied in PBS

• Modification:

  None

• Shipping Conditions:

  Dry Ice

• Storage Conditions:

  Store vial at -20˚ C

• Fragment:

  IgG2a

• Specificity:

  NK1.1

• Applications Notes:

  NK1.1 Antibody [PK136] for use in flow cytometry, immunohistochemistry, immunoprecipitation, depletion, CMCD, blocking, and activation assays.

• Symbol:

  Klrb1c

• NCBI Official Name:

  Killer cell lectin-like receptor subfamily B member 1C

• NCBI Organism:

  Mus musculus

• Other Product Names:

  Ly-55, CD161b/CD161c

• Tested Applications:

  IHC-Fr, Flow

• Physical Properties:

  Liquid