FER (phospho Tyr402) Antibody

• Background:

  Fer protein is a member of the FPS/FES family of nontransmembrane receptor tyrosine kinases. It regulates cell-cell adhesion and mediates signaling from the cell surface to the cytoskeleton via growth factor receptors.

• NCBI Gene ID:

  2241

• Swiss Prot:

  P16591

• Accession Number:

  NP_005237.2

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  FER (phospho Tyr402) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 402 (V-N-Y (p) -E-E) derived from Human FER .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Phospho-Specific

• Purification:

  Antibodies were purified by affinity-chromatography using epitope-specific peptide.

• Concentration:

  1 mg/mL

• Buffer:

  Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Modification:

  Phospho-Specific

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store antibody at -20˚ C for up to one year.

• Calculated Molecular Weight:

  85 kDa

• Fragment:

  IgG

• Specificity:

  The antibody detects endogenous levels of FER only when phosphorylated at tyrosine 402.

• Applications Notes:

  Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

• Symbol:

  FER

• NCBI Official Name:

  Fer (fps/fes related) tyrosine kinase

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Hao Q.-L., Mol. Cell. Biol. 9:1587-1593 (1989) .

• Background Reference 02:

  Lee S.-T., Oncogene 8:3403-3410 (1993) .

• Background Reference 03:

  Krolewski J.J., Oncogene 5:277-282 (1990) .

• Other Product Names:

  FER, FERT2, TYK3, p94-FER

• Tested Applications:

  WB, IHC

• Protein ID:

  97536202

• Physical Properties:

  Liquid