NK1.1 Antibody [PK136]

• Background:

  The PK136 monoclonal antibody is specific for the mouse NK1.1, a receptor from the killer cell lectin-like receptor (KLR) family. Nk1.1 is an antigen encoded by the Klrb1c/NKR-P1C gene expressed by the natural killer cells of some selected strains of mice (C57BL, FVB/N, NZB) and encoded by the Klrb1b/NKR-P1B gene expressed on Swiss NIH and SJL mice. Pk136 binds to an epitope common to NKR-P1B and NKR-P1C.The Klrb1 is a family of type II transmembrane C-type lectin receptors. Klrb1c activates the NK-cell cytotoxicity, while Klrb1b inhibits it. PK136 is useful in defining the NK cells and the rare population of NK-T lymphocytes and specific cultured monocytes.

• NCBI Gene ID:

  17059

• Swiss Prot:

  P27814

• Host:

  Mouse

• Reactivity:

  Mouse

• Clonality:

  Monoclonal

• Clone:

  PK136

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Innate Immunity

• Purification:

  The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.

• Concentration:

  Batch dependent

• Buffer:

  Phosphate-buffered aqueous solution, ph7.2.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  The product should be stored undiluted at 4˚ C . Do not freeze.

• Fragment:

  Mouse IgG2a, kappa

• Specificity:

  The PK136 monoclonal antibody is specific for the mouse NK1.1, a receptor from the killer cell lectin-like receptor (KLR) family.

• Symbol:

  Klrb1c

• NCBI Official Name:

  Killer cell lectin-like receptor subfamily B member 1C

• NCBI Organism:

  Mus musculus

• Other Product Names:

  Nk1, Ly59, Nk-1, CD161, Ly-59, Ly55c, NK1.1, NKRP1, Nk1.2, NK-RP1, Nk-1.2, Nkrp1c, ly-55c, NKRP140, AI462337, NKR-P1.9, Klrb1c

• Tested Applications:

  Flow, Functional Assays, IHC, IF, IP

• Physical Properties:

  Liquid