CD15 Antibody [HI98] (FITC)

• Background:

  The HI98 monoclonal antibody specifically reacts with CD15, a 220 kDa carbohydrate moiety also known as SSEA-1, Lewis 3-fucosyl-N-acetyllactosamine (3-FAL) . CD15 is expressed on most granulocytes and monocytes to the exclusion of lymphocytes and basophils. It is involved in cell adhesion, chemotaxis, and phagocytosis.

• NCBI Gene ID:

  2526

• Swiss Prot:

  P22083

• Host:

  Mouse

• Reactivity:

  Human

• Clonality:

  Monoclonal

• Clone:

  HI98

• Conjugation:

  FITC

• Type:

  Primary Antibodies

• Field of Research:

  Innate Immunity, Stem Cell

• Purification:

  The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

• Concentration:

  Batch dependent

• Buffer:

  Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

• Fragment:

  Mouse IgM, kappa

• Specificity:

  The HI98 monoclonal antibody specifically reacts with CD15, a 220 kDa carbohydrate moiety also known as SSEA-1, Lewis 3-fucosyl-N-acetyllactosamine (3-FAL) .

• Symbol:

  FUT4

• NCBI Official Name:

  Fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.

• Background Reference 02:

  Barclay, A. N., Brown, M. H., Law, S. A. K. A., McKnight, A. J., Tomlinson, M. G., van der Merwe, P. A. (1997) .The leucocyte antigen factsbook. Academic Press.

• Background Reference 03:

  Lund-Johansen, F., Olweus, J., Horejsi, V., Skubitz, K. M., Thompson, J. S., Vilella, R., Symington, F. W. (1992) . Activation of human phagocytes through carbohydrate antigens (CD15, sialyl-CD15, CDw17, and CDw65) .Journal of immunology (Baltimore, Md.: 1950),148 (10), 3221.

• Other Product Names:

  LeX, CD15, ELFT, FCT3A, FUTIV, SSEA-1, FUC-TIV, FUT4

• Tested Applications:

  Flow

• Physical Properties:

  Liquid