SHP 1 (Ab 536) Antibody

• Background:

  Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus.

• NCBI Gene ID:

  5777

• Swiss Prot:

  P29350

• Accession Number:

  NP_002822.2

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  SHP-1 (Ab-536) antibody was raised against a peptide sequence around aa.534~538 (S-E-Y-G-N) derived from Human SHP-1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Antibodies were purified by affinity-chromatography using epitope-specific peptide.

• Concentration:

  1 mg/mL

• Buffer:

  Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store antibody at -20˚ C for up to one year.

• Calculated Molecular Weight:

  68 kDa

• Specificity:

  This antibody detects endogenous level of total SHP-1 protein.

• Applications Notes:

  Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200

• Symbol:

  PTPN6

• NCBI Official Name:

  Protein tyrosine phosphatase, non-receptor type 6

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Migone TS, et al. (1998) Proc Natl Acad Sci USA; 95 (7) : 3845-3850. Timms JF, et al. (1998) Mol Cell Biol; 18 (7) : 3838-3850. Kanagasundaram V, et al. (1999) Mol Cell Biol; 19 (6) : 4079-4092. Hauck CR, et al. (1999) Infect Immun; 67 (10) : 5490-5494.

• Other Product Names:

  HCP, HCPH, SHP1, SHP-1, HPTP1C, PTP-1C, SHP-1L, SH-PTP1, BLIMP1, 70Z-SHP, EC 3.1.3.48, HCP, Hematopoietic cell protein-tyrosine phosphatase

• Tested Applications:

  WB, IHC, IF

• Protein ID:

  18104989

• Physical Properties:

  Liquid