IL-27 Antibody

• Background:

  IL-27 is a cytokine that shares the sequence similarity with IL17. The treatment of endothelial cells with this cytokine has been shown to stimulate the production of other cytokines including IL6, IL8 and CSF2/ GM-CSF. The increased expression of IL8 induced by this cytokine was found to be NF-kappa B-dependent.

• NCBI Gene ID:

  53342

• Swiss Prot:

  Q8TAD2

• Accession Number:

  Q8TAD2

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This IL-27 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 57-87 amino acids from the Central region of human IL-27.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Immunology

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  22 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  IL17D

• NCBI Official Name:

  Interleukin-17D

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Clark, H.F., et al., Genome Res. 13 (10) :2265-2270 (2003) .

• Background Reference 02:

  Starnes, T., et al., J. Immunol. 169 (2) :642-646 (2002) .

• Other Product Names:

  Interleukin-17D, IL-17D, Interleukin-27, IL-27, IL17D, IL27

• Tested Applications:

  WB, IHC-P, Flow

• Protein ID:

  46576614

• Physical Properties:

  Liquid