RHOBTB1 Antibody

• Background:

  The protein encoded by this gene belongs to the Rho family of the small GTPase superfamily. It contains a GTPase domain, a proline-rich region, a tandem of 2 BTB (broad complex, tramtrack, and bric-a-brac) domains, and a conserved C-terminal region. The protein plays a role in small GTPase-mediated signal transduction and the organization of the actin filament system. Alternate splicing results in multiple transcript variants. [provided by RefSeq].

• NCBI Gene ID:

  9886

• Swiss Prot:

  O94844

• Accession Number:

  O94844

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This RHOBTB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 623-650 amino acids from the C-terminal region of human RHOBTB1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  79 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  RHOBTB1

• NCBI Official Name:

  Rho-related BTB domain-containing protein 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Newton-Cheh, C., et al. Nat. Genet. (2009) In press :

• Background Reference 02:

  Grupe, A., et al. Am. J. Hum. Genet. 78 (1) :78-88 (2006)

• Background Reference 03:

  Beder, L.B., et al. J. Cancer Res. Clin. Oncol. 132 (1) :19-27 (2006)

• Background Reference 04:

  Aspenstrom, P., et al. Biochem. J. 377 (PT 2), 327-337 (2004) :

• Other Product Names:

  Rho-related BTB domain-containing protein 1, RHOBTB1, KIAA0740

• Tested Applications:

  WB

• Physical Properties:

  Liquid