TAS1R1 Antibody

• Background:

  The protein encoded by this gene is a G protein-coupled receptor and is a component of the heterodimeric amino acid taste receptor T1R1+3. The T1R1+3 receptor responds to L-amino acids but not to D-enantiomers or other compounds. Most amino acids that are perceived as sweet activate T1R1+3, and this activation is strictly dependent on an intact T1R1+3 heterodimer. Multiple transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID:

  80835

• Swiss Prot:

  Q7RTX1

• Accession Number:

  Q7RTX1

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This TAS1R1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 323-351 amino acids from the Central region of human TAS1R1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience, Signal Transduction, Growth Factors

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  93 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  TAS1R1

• NCBI Official Name:

  Taste receptor type 1 member 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Fushan, A.A., et al. Chem. Senses 35 (7) :579-592 (2010)

• Background Reference 02:

  Pinheiro, A.P., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :

• Background Reference 03:

  Prezeau, L., et al. Curr Opin Pharmacol 10 (1) :6-13 (2010)

• Background Reference 04:

  Chandrashekar, J., et al. Nature 444 (7117) :288-294 (2006)

• Other Product Names:

  Taste receptor type 1 member 1, G-protein coupled receptor 70, TAS1R1, GPR70, T1R1, TR1

• Tested Applications:

  WB

• Protein ID:

  57013075

• Physical Properties:

  Liquid