FBLN1 Antibody

• Background:

  Fibulin 1 is a secreted glycoprotein that becomes incorporated into a fibrillar extracellular matrix. Calcium-binding is apparently required to mediate its binding to laminin and nidogen. It mediates platelet adhesion via binding fibrinogen. Four splice variants which differ in the 3' end have been identified. Each variant encodes a different isoform, but no functional distinctions have been identified among the four variants.

• NCBI Gene ID:

  2192

• Swiss Prot:

  P23142

• Accession Number:

  P23142

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This FBLN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 622-650 amino acids from the C-terminal region of human FBLN1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  77 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  FBLN1

• NCBI Official Name:

  Fibulin-1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

• Background Reference 02:

  Li, C., et al. Mol. Vis. 16, 689-697 (2010) :

• Background Reference 03:

  Wooten, E.C., et al. PLoS ONE (1), E8830 (2010) :

• Background Reference 04:

  Argraves, W.S., et al. Histochem. Cell Biol. 132 (5) :559-565 (2009)

• Other Product Names:

  Fibulin-1, FIBL-1, FBLN1

• Tested Applications:

  WB, IHC-P

• Protein ID:

  215274249

• Physical Properties:

  Liquid