TRAIL-R3 Antibody [HS301]

• Background:

  TRAIL-R3 is a receptor for the cytotoxic ligand TRAIL. It lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis. Protects cells against TRAIL mediated apoptosis by competing with TRAIL-R1 and R2 for binding to the ligand.

• NCBI Gene ID:

  8794

• Swiss Prot:

  O14798

• Accession Number:

  2338421

• Host:

  Mouse

• Reactivity:

  Human

• Immunogen:

  Recombinant human TRAIL-R3 (DcR1) .

• Clonality:

  Monoclonal

• Clone:

  HS301

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Immunology

• Purification:

  >95% (SDS-PAGE)

• Concentration:

  1 mg/ml

• Buffer:

  Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Stable for at least 1 year after receipt when stored at -20˚ C.

• Fragment:

  IgG1

• Specificity:

  Recognizes human TRAIL-R3. Does not cross-react with human TRAIL-R1, -R2 or -R4.

• Applications Notes:

  Definition for 1 test: 1ul of labeled antibody in 200ul of Flow Cytometry buffer (see online protocol) .

• Symbol:

  TNFRSF10C

• NCBI Official Name:

  Tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  TRAIL Receptor 3; DcR1; TRID; TNFRSF10C; CD263

• Tested Applications:

  Flow, ICC

• Protein ID:

  AF012536

• Physical Properties:

  Liquid