Resistin Antibody [MRES 06]

• Background:

  The adipocytokine resistin which belongs to a family of cysteine-rich C-terminal proteins known as resistin-like molecules (RELM; RELMalpha/FIZZ 1 and RELMbeta/FIZZ 2) of FIZZ (found in inflammatory zone) are thought to be involved in inflammatory processes. Previous studies in mice showed that resistin impairs glucose tolerance and insulin action. In addition, resistin also inhibits adipogenesis in murine 3T3-L1 cells. Therefore resistin has also been proposed as an adipocyte-secreted factor thought to link obesity and T2DM.

• NCBI Gene ID:

  57264

• Swiss Prot:

  Q99P87

• Accession Number:

  12667798

• Host:

  Rat

• Reactivity:

  Mouse

• Immunogen:

  Recombinant mouse resistin.

• Clonality:

  Monoclonal

• Clone:

  MRES 06

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Obesity

• Concentration:

  1 mg/ml

• Buffer:

  Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Stable for at least 1 year after receipt when stored at -20˚ C.

• Fragment:

  IgG2a, kappa

• Specificity:

  Recognizes mouse resistin. Detects a band of ~14kDa by Western blot. Does not cross-react with human resistin.

• Applications Notes:

  ELISA: (direct or indirect: 1:5,000-1:10,000) . Western blot: (1:5,000-1:10,000 using ECL. Suggested blocking and dilution buffer is TBST with 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at rooom temperature) . Optimal conditions should be determined individually for each application.

• Symbol:

  Retn

• NCBI Official Name:

  Resistin

• NCBI Organism:

  Mus musculus

• Other Product Names:

  FIZZ3; Found in Inflammatory Zone 3; ADSF; Adipose Tissue-Specific Secretory Factor

• Tested Applications:

  ELISA, WB

• Protein ID:

  NP_075360.1

• Physical Properties:

  Liquid