Recombinant IgG Heavy Chain Antibody [IG507R]

• Background:

  Recognizes a protein of 75kDa, identified as gamma heavy chain of human immunoglobulins. It reacts with all sub-classes of gamma chain of human immunoglobulins. It does not cross-react with alpha (IgA), mu (IgM), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This mAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.

• NCBI Gene ID:

  3500

• Swiss Prot:

  P01857

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Human Ig Gamma Chain was used as the immunogen for this recombinant IgG antibody.

• Clonality:

  Recombinant Monoclonal

• Clone:

  IG507R

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Immunology

• Purification:

  Protein A affinity chromatography

• Concentration:

  0.2 mg/mL

• Buffer:

  PBS with 0.1 mg/ml BSA and 0.05% sodium azide

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.

• Fragment:

  IgG, kappa

• Applications Notes:

  1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

• Symbol:

  IGHG1

• NCBI Official Name:

  Immunoglobulin heavy constant gamma 1 (G1m marker)

• NCBI Organism:

  Homo sapiens

• Tested Applications:

  WB, Flow, IF, IHC-P

• Physical Properties:

  Liquid