Blood Group Lewis y Antibody [A70-A/A9]

• Background:

  This antibody recognizes a carbohydrate epitope present on tumor-associated Lewis y antigen (Fucalpha1-2Galbeta1-4/3[Fucalpha1-3/4]GlcNAcbeta-) . Lewis y is expressed in large bowel tumors and colorectal carcinomas. It may be useful in the classification of human renal and bladder tumors. The Lewis y antigen has been evaluated as a clinical marker for the diagnosis and prognosis of cholangiocarcinoma, hepatocellular carcinoma and breast cancer.

• Swiss Prot:

  NotApplicable

• Host:

  Mouse

• Reactivity:

  Human

• Immunogen:

  Live Ls174T cells (human colon carcinoma) were used as the immunogen for the Lewis y antibody.

• Clonality:

  Monoclonal

• Clone:

  A70-A/A9

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Protein G affinity chromatography

• Concentration:

  0.2 mg/mL

• Buffer:

  PBS with 0.1 mg/ml BSA and 0.05% sodium azide

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.

• Fragment:

  IgG1, kappa

• Tested Applications:

  Flow, IF, IHC-P

• Physical Properties:

  Liquid