RNASEL Antibody

• Background:

  This gene encodes a component of the interferon-regulated 2-5A system that functions in the antiviral and antiproliferative roles of interferons. Mutations in this gene have been associated with predisposition to prostate cancer and this gene is a candidate for the hereditary prostate cancer 1 (HPC1) allele.

• NCBI Gene ID:

  6041

• Swiss Prot:

  Q05823

• Accession Number:

  NP_066956

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RNASEL.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Signal Transduction

• Purification:

  Antibody is purified by Protein A/G affinity chromatography method.

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store RNASEL antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  84 kDa

• Applications Notes:

  RNASEL antibody can be used for detection of RNASEL by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  RNASEL

• NCBI Official Name:

  Ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Nakazato, H., et al., (2003) Br. J. Cancer 89 (4), 691-696..

• Other Product Names:

  RNASEL, RNS4, PRCA1

• Tested Applications:

  WB

• Protein ID:

  10863929

• Physical Properties:

  Liquid